相互作用
Atenolol + Bismuth subsalicylate
重症度: 中等度
Atenolol and Bismuth subsalicylate: moderate interaction.
最終更新日
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概要
Bismuth subsalicylate releases salicylate, which may inhibit renal prostaglandin synthesis, causing sodium and water retention and blunting the antihypertensive effect of beta-blockers. The effect is chiefly seen with regular high-dose salicylate use and is generally modest with short courses.
この相互作用をわかりやすく説明すると
Atenolol and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atenolol belongs to Cardiovascular; Bismuth subsalicylate belongs to Gastrointestinal Tract.
なぜ起こるのか
Salicylate inhibits prostaglandin synthesis, causing sodium and fluid retention that opposes the antihypertensive effect.
対処法
Limit bismuth subsalicylate to short courses and monitor blood pressure if used repeatedly. Use an alternative antidiarrheal or antacid for prolonged treatment.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、AtenololとBismuth subsalicylateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Bismuth subsalicylateのその他の相互作用
Atenololのその他の相互作用
よくある質問
Can I take Atenolol with Bismuth subsalicylate?
MediHelp rates the interaction as moderate. Atenolol and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bismuth subsalicylate releases salicylate, which may inhibit renal prostaglandin synthesis, causing sodium and water retention and blunting the antihypertensive effect of beta-blockers. The effect is chiefly seen with regular high-dose salicylate use and is generally modest with short courses.
How serious is the interaction between Atenolol and Bismuth subsalicylate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Limit bismuth subsalicylate to short courses and monitor blood pressure if used repeatedly. Use an alternative antidiarrheal or antacid for prolonged treatment.
What other medicines interact with Bismuth subsalicylate?
MediHelp also lists interactions of Bismuth subsalicylate with, for example, Dichlorphenamide, Warfarin, Acetylsalicylic acid. The full list is on the Bismuth subsalicylate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
