医薬品リファレンス
Bismuth subsalicylate
Bismuth subsalicylate is a medicine in the class gastrointestinal tract. It is used for diarrhea.
- 薬効分類: Gastrointestinal Tract
- 効能・効果: diarrhea
最終更新日 出典: US FDA label
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要点
- 薬効分類
- Gastrointestinal Tract
- 一般的な剤形
- 錠剤, 溶液, 経口懸濁液, カプセル剤, 散剤
- 一般的な規格
- 262 mg, 525 mg/30 ml, 525 mg/15 ml
- 既知の相互作用
- 35 (重大: 2 · 中等度: 24 · 軽度: 9)
- 商品名
- 133
- 国・市場
- 2
何に使われるか
作用のしくみ
Antimicrobial, anti-inflammatory action (bismuth); antisecretory effect (salicylate).
成人の通常用量（添付文書の要約）
Diarrhea, Gas, Upset Stomach, Indigestion, Heartburn, Nausea:2 tablets (262 mg/tab) or 30 mL every hour; maximum daily dose: 8 regular-strength doses or 4 extra-strength doses.
妊娠と授乳
- 妊娠
- Unsafe The salicylate part is absorbed and acts like aspirin: risk of fetal kidney problems, low amniotic fluid and ductus closure later in pregnancy, and bleeding near term. Avoid in pregnancy; use oral rehydration and, if needed, loperamide.
- 授乳
- Unsafe No direct data; salicylate may pass to the infant through milk. LactMed prefers alternatives. Avoid; use rehydration or loperamide if needed.
報告されている副作用
- Diarrhea
- Nausea
- Abdominal pain
- Melena
禁忌
- Hypersensitivity to bismuth, aspirin, other salicylates
- Infectious diarrhea, high fever, von Willebrand disease, hemorrhage, ulcer or GI bleeding with black or bloody stool, hemophilia
- In pediatric patients, chicken pox or influenza (risk of Reye syndrome)
注意が必要な方
- Bismuth subcitrate potassium may cause temporary and harmless darkening of tongue and/or black stools, generally reversible within several days after treatment stopped.
- Bismuth absorbs x-rays and may interfere with x-ray diagnostic procedures of gastrointestinal tract.
- Not to be administered to children or teenagers recovering from flu-like symptoms or chickenpox; increased incidence of Reye syndrome, associated with salicylate products
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (35)
- Bismuth subsalicylate + Dichlorphenamide Major
- Bismuth subsalicylate + Warfarin Major
- Acetylsalicylic acid + Bismuth subsalicylate Moderate
- Amlodipine-benazepril + Bismuth subsalicylate Moderate
- Aspirin + Bismuth subsalicylate Moderate
- Aspirin / citric acid / sodium bicarbonate + Bismuth subsalicylate Moderate
- Aspirin rectal + Bismuth subsalicylate Moderate
- Atenolol + Bismuth subsalicylate Moderate
- Benazepril + Bismuth subsalicylate Moderate
- Betaxolol + Bismuth subsalicylate Moderate
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Bismuth subsalicylateの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Dosing in older adults
- How to give it
- Pharmacokinetics
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Bismuth subsalicylate used for?
Bismuth subsalicylate is a medicine in the class gastrointestinal tract. It is used for Diarrhea, Helicobacter pylori bacteria, Indigestion, Traveler's diarrhea.
What side effects have been reported with Bismuth subsalicylate?
Diarrhea, Nausea, Abdominal pain, Melena.
Can Bismuth subsalicylate be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. The salicylate part is absorbed and acts like aspirin: risk of fetal kidney problems, low amniotic fluid and ductus closure later in pregnancy, and bleeding near term. Avoid in pregnancy; use oral rehydration and, if needed, loperamide. Breastfeeding: Unsafe. No direct data; salicylate may pass to the infant through milk. LactMed prefers alternatives. Avoid; use rehydration or loperamide if needed.
What does Bismuth subsalicylate interact with?
MediHelp lists 35 known interactions for Bismuth subsalicylate. Major: 2 · Moderate: 24 · Minor: 9. The most serious include Dichlorphenamide, Warfarin, Acetylsalicylic acid.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
