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相互作用

Atropine + Trospium

重症度: 中等度

Atropine and Trospium: moderate interaction.

最終更新日

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概要

Atropine is a systemic antimuscarinic and adds to trospium's effects. This can cause dry mouth, constipation, urinary retention, tachycardia, blurred vision and confusion.

この相互作用をわかりやすく説明すると

Atropine and Trospium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Atropine belongs to Miscellaneous; Trospium belongs to Genitourinary.

エビデンスレベル: Moderate

なぜ起こるのか

Additive antimuscarinic pharmacodynamic effects.

対処法

Monitor for anticholinergic toxicity such as urinary retention and tachycardia. Reduce doses or avoid the combination in patients at risk, such as the elderly.

薬剤師に尋ねること

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、AtropineとTrospiumの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Atropine with Trospium?

MediHelp rates the interaction as moderate. Atropine and Trospium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atropine is a systemic antimuscarinic and adds to trospium's effects. This can cause dry mouth, constipation, urinary retention, tachycardia, blurred vision and confusion.

How serious is the interaction between Atropine and Trospium?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic toxicity such as urinary retention and tachycardia. Reduce doses or avoid the combination in patients at risk, such as the elderly.

What other medicines interact with Trospium?

MediHelp also lists interactions of Trospium with, for example, Clozapine, Pramlintide, Thioridazine. The full list is on the Trospium page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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