相互作用
Atropine iv / + Umeclidinium
重症度: 中等度
Atropine iv / and Umeclidinium: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Systemic atropine adds antimuscarinic effects to inhaled umeclidinium. Tachycardia, dry mouth, urinary retention and constipation may be increased, though single clinical doses of atropine are usually tolerated.
この相互作用をわかりやすく説明すると
Atropine iv / and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Additive muscarinic receptor antagonism.
対処法
Monitor heart rate and for urinary retention when atropine is given, especially with repeated doses. Avoid long-term combination of systemic antimuscarinics with umeclidinium where possible.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Atropine iv /とUmeclidiniumの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を7日間無料でお試し。カード登録不要。
Umeclidiniumのその他の相互作用
よくある質問
Can I take Atropine iv / with Umeclidinium?
MediHelp rates the interaction as moderate. Atropine iv / and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Systemic atropine adds antimuscarinic effects to inhaled umeclidinium. Tachycardia, dry mouth, urinary retention and constipation may be increased, though single clinical doses of atropine are usually tolerated.
How serious is the interaction between Atropine iv / and Umeclidinium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor heart rate and for urinary retention when atropine is given, especially with repeated doses. Avoid long-term combination of systemic antimuscarinics with umeclidinium where possible.
What other medicines interact with Umeclidinium?
MediHelp also lists interactions of Umeclidinium with, for example, Tiotropium, Aclidinium, Atropine. The full list is on the Umeclidinium page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
