相互作用
Dicyclomine + Umeclidinium
重症度: 中等度
Dicyclomine and Umeclidinium: moderate interaction.
最終更新日
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概要
Dicyclomine is an antimuscarinic antispasmodic, so combining it with umeclidinium may increase anticholinergic adverse effects including dry mouth, constipation, urinary retention, blurred vision and tachycardia. Systemic umeclidinium exposure is low, but additive effects are possible in vulnerable patients.
この相互作用をわかりやすく説明すると
Dicyclomine and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dicyclomine belongs to Respiratory; Umeclidinium belongs to Respiratory.
なぜ起こるのか
Additive antimuscarinic pharmacodynamic effects.
対処法
Avoid unnecessary duplication of anticholinergic therapy, and monitor for urinary retention, constipation and eye symptoms, particularly in older patients.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DicyclomineとUmeclidiniumの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Umeclidiniumのその他の相互作用
Dicyclomineのその他の相互作用
よくある質問
Can I take Dicyclomine with Umeclidinium?
MediHelp rates the interaction as moderate. Dicyclomine and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dicyclomine is an antimuscarinic antispasmodic, so combining it with umeclidinium may increase anticholinergic adverse effects including dry mouth, constipation, urinary retention, blurred vision and tachycardia. Systemic umeclidinium exposure is low, but additive effects are possible in vulnerable patients.
How serious is the interaction between Dicyclomine and Umeclidinium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unnecessary duplication of anticholinergic therapy, and monitor for urinary retention, constipation and eye symptoms, particularly in older patients.
What other medicines interact with Umeclidinium?
MediHelp also lists interactions of Umeclidinium with, for example, Tiotropium, Aclidinium, Atropine iv /. The full list is on the Umeclidinium page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
