相互作用
Belladonna alkaloids + Umeclidinium
重症度: 中等度
Belladonna alkaloids and Umeclidinium: moderate interaction.
最終更新日
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概要
Belladonna alkaloids such as atropine, hyoscyamine and scopolamine are antimuscarinic and add to the effects of umeclidinium. This can cause dry mouth, constipation, urinary retention, tachycardia and confusion in older adults.
この相互作用をわかりやすく説明すると
Belladonna alkaloids and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Additive muscarinic receptor antagonism.
対処法
Avoid concurrent use where an alternative exists. If needed, monitor for urinary retention, constipation and CNS effects, particularly in older patients.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Belladonna alkaloidsとUmeclidiniumの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Umeclidiniumのその他の相互作用
よくある質問
Can I take Belladonna alkaloids with Umeclidinium?
MediHelp rates the interaction as moderate. Belladonna alkaloids and Umeclidinium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Belladonna alkaloids such as atropine, hyoscyamine and scopolamine are antimuscarinic and add to the effects of umeclidinium. This can cause dry mouth, constipation, urinary retention, tachycardia and confusion in older adults.
How serious is the interaction between Belladonna alkaloids and Umeclidinium?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where an alternative exists. If needed, monitor for urinary retention, constipation and CNS effects, particularly in older patients.
What other medicines interact with Umeclidinium?
MediHelp also lists interactions of Umeclidinium with, for example, Tiotropium, Aclidinium, Atropine iv /. The full list is on the Umeclidinium page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
