医薬品リファレンス
Umeclidinium
Umeclidinium is a medicine in the class respiratory. It is used for copd.
- 薬効分類: Respiratory
- 効能・効果: copd
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
要点
- 薬効分類
- Respiratory
- ATCコード
- R03BB07
- 一般的な剤形
- 吸入器
- 一般的な規格
- 62.5 mcg
- 既知の相互作用
- 27 (重大: 1 · 中等度: 21 · 軽度: 5)
- 商品名
- 5
- 国・市場
- 3
何に使われるか
作用のしくみ
Long-acting muscarinic antagonist (LAMA) often referred to as an anticholinergic; blocks action of acetylcholine at muscarinic receptors (M1 to M5) in the bronchial airways (M3) by preventing increase in intracellular calcium concentration, leading to relaxation of airway smooth muscle, improved lung function, and decreased mucus secretion.
成人の通常用量（添付文書の要約）
COPD: 62.5 mcg (1 actuation) inhaled once a Day.
妊娠と授乳
- 妊娠
- Unknown Inhaled; insufficient human data. No harm in rats or rabbits at about 50 to 200 times human exposure. Use only if the benefit outweighs the risk; poorly controlled COPD or asthma is a greater risk.
- 授乳
- Safe No human milk data. Inhalation gives low blood levels and any drug in milk would not be absorbed by the infant. US label: weigh benefits. LactMed: small risk; breastfeeding can be continued.
報告されている副作用
- Upper respiratory tract infection
- Nasopharyngitis
- Arthralgia
- Cough
- Toothache
禁忌
- Severe hypersensitivity to milk proteins
- Demonstrated hypersensitivity to umeclidinium or any of the excipients
注意が必要な方
- Contraindicated in people with Severe hypersensitivity to milk proteins
- Worsening of narrow-angle glaucoma may occur
- Paradoxical bronchospasm reported; discontinue and treat immediately with an inhaled, prompt-acting bronchodilator (eg, albuterol)
妊娠中または授乳中であること、腎臓や肝臓の病気、アレルギー、ほかに使用しているすべての薬やサプリメントについて、薬剤師または医師にお伝えください。
主な相互作用 (27)
- Tiotropium + Umeclidinium Major
- Aclidinium + Umeclidinium Moderate
- Atropine + Umeclidinium Moderate
- Atropine iv / + Umeclidinium Moderate
- Belladonna alkaloids + Umeclidinium Moderate
- Bethanechol + Umeclidinium Moderate
- Dicyclomine + Umeclidinium Moderate
- Donepezil transdermal + Umeclidinium Moderate
- Glycopyrrolate + Umeclidinium Moderate
- Glycopyrrolate inhaled + Umeclidinium Moderate
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Umeclidiniumの完全なモノグラフ（用量、妊娠・授乳、副作用、警告、すべての相互作用）を表示できます。
- Dosing by age, kidney and liver function, and further dose lines
- Renal and hepatic dose adjustments
- Paediatric dosing
- Pharmacokinetics
- Patient counselling points
- Food interactions
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同じ分類のほかの薬剤
よくある質問
What is Umeclidinium used for?
Umeclidinium is a medicine in the class respiratory. It is used for COPD.
What side effects have been reported with Umeclidinium?
Upper respiratory tract infection, Nasopharyngitis, Arthralgia, Cough, Toothache.
Can Umeclidinium be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Inhaled; insufficient human data. No harm in rats or rabbits at about 50 to 200 times human exposure. Use only if the benefit outweighs the risk; poorly controlled COPD or asthma is a greater risk. Breastfeeding: Safe. No human milk data. Inhalation gives low blood levels and any drug in milk would not be absorbed by the infant. US label: weigh benefits. LactMed: small risk; breastfeeding can be continued.
What does Umeclidinium interact with?
MediHelp lists 27 known interactions for Umeclidinium. Major: 1 · Moderate: 21 · Minor: 5. The most serious include Tiotropium, Aclidinium, Atropine.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
