相互作用
Bexagliflozin + Glipizide-metformin
重症度: 中等度
Bexagliflozin and Glipizide-metformin: moderate interaction.
最終更新日
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概要
Bexagliflozin adds glucose-lowering effect to glipizide, which raises the risk of hypoglycemia. It also promotes volume depletion, which matters in patients on metformin.
この相互作用をわかりやすく説明すると
Bexagliflozin and Glipizide-metformin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Bexagliflozin belongs to Endocrine; Glipizide-metformin belongs to Endocrine.
なぜ起こるのか
Additive glucose lowering from SGLT2 inhibition and insulin secretagogue action.
対処法
Consider reducing the glipizide dose when starting bexagliflozin and monitor blood glucose and hydration status.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、BexagliflozinとGlipizide-metforminの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Glipizide-metforminのその他の相互作用
Bexagliflozinのその他の相互作用
よくある質問
Can I take Bexagliflozin with Glipizide-metformin?
MediHelp rates the interaction as moderate. Bexagliflozin and Glipizide-metformin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bexagliflozin adds glucose-lowering effect to glipizide, which raises the risk of hypoglycemia. It also promotes volume depletion, which matters in patients on metformin.
How serious is the interaction between Bexagliflozin and Glipizide-metformin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider reducing the glipizide dose when starting bexagliflozin and monitor blood glucose and hydration status.
What other medicines interact with Glipizide-metformin?
MediHelp also lists interactions of Glipizide-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Glipizide-metformin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
