相互作用
Calcium chloride + Ceftriaxone
重症度: 併用禁忌
Calcium chloride and Ceftriaxone: contraindicated interaction.
最終更新日
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概要
Ceftriaxone forms insoluble precipitates with calcium, and fatal crystalline deposits in the lungs and kidneys have occurred in neonates given both IV. Labeling contraindicates the combination in neonates and in any patient when mixed in the same line.
この相互作用をわかりやすく説明すると
Calcium chloride and Ceftriaxone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
なぜ起こるのか
Ceftriaxone binds calcium to form insoluble calcium-ceftriaxone salt that precipitates in lines and tissues.
対処法
Do not give ceftriaxone to neonates needing IV calcium, and never mix the two or co-infuse through one line. In older patients, give sequentially only after thoroughly flushing the line with a compatible fluid.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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アカウントを作成してPro+トライアルを始めると、Calcium chlorideとCeftriaxoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ceftriaxoneのその他の相互作用
よくある質問
Can I take Calcium chloride with Ceftriaxone?
MediHelp rates the interaction as contraindicated. Calcium chloride and Ceftriaxone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ceftriaxone forms insoluble precipitates with calcium, and fatal crystalline deposits in the lungs and kidneys have occurred in neonates given both IV. Labeling contraindicates the combination in neonates and in any patient when mixed in the same line.
How serious is the interaction between Calcium chloride and Ceftriaxone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give ceftriaxone to neonates needing IV calcium, and never mix the two or co-infuse through one line. In older patients, give sequentially only after thoroughly flushing the line with a compatible fluid.
What other medicines interact with Ceftriaxone?
MediHelp also lists interactions of Ceftriaxone with, for example, Calcium gluconate, Calcium, Lactated ringer's. The full list is on the Ceftriaxone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
