相互作用
Cilastatin-imipenem + Microbiota
重症度: 中等度
Cilastatin-imipenem and Microbiota: moderate interaction.
最終更新日
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概要
Oral microbiota spore products require live bacteria to colonize the gut. Imipenem is a broad-spectrum carbapenem that may kill the administered organisms and reduce efficacy. Careful timing after antibiotic therapy is needed.
この相互作用をわかりやすく説明すると
Cilastatin-imipenem and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
なぜ起こるのか
Antibacterial activity against the live bacterial content impairs engraftment.
対処法
Finish antibiotic therapy and observe the labeled washout interval before administering the microbiota product. Avoid concurrent systemic antibiotics where possible.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Cilastatin-imipenemとMicrobiotaの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Cilastatin-imipenemのその他の相互作用
よくある質問
Can I take Cilastatin-imipenem with Microbiota?
MediHelp rates the interaction as moderate. Cilastatin-imipenem and Microbiota can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral microbiota spore products require live bacteria to colonize the gut. Imipenem is a broad-spectrum carbapenem that may kill the administered organisms and reduce efficacy. Careful timing after antibiotic therapy is needed.
How serious is the interaction between Cilastatin-imipenem and Microbiota?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Finish antibiotic therapy and observe the labeled washout interval before administering the microbiota product. Avoid concurrent systemic antibiotics where possible.
What other medicines interact with Cilastatin-imipenem?
MediHelp also lists interactions of Cilastatin-imipenem with, for example, Divalproex, Ganciclovir, Valproic acid. The full list is on the Cilastatin-imipenem page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
