相互作用
Ciprofloxacin + Macimorelin
重症度: 重大
Ciprofloxacin and Macimorelin: major interaction.
最終更新日
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概要
Macimorelin causes a small QT prolongation, and ciprofloxacin also prolongs QT, so the combination may increase arrhythmia risk during the growth hormone stimulation test. The test is single-dose, which limits exposure.
この相互作用をわかりやすく説明すると
Ciprofloxacin and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Ciprofloxacin belongs to Anti Bacterial; Macimorelin belongs to Endocrine.
なぜ起こるのか
Additive pharmacodynamic QT prolongation.
対処法
Postpone the macimorelin test until ciprofloxacin has been stopped and cleared, or use another diagnostic option. If unavoidable, obtain an ECG and correct electrolytes.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、CiprofloxacinとMacimorelinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ciprofloxacinのその他の相互作用
Macimorelinのその他の相互作用
よくある質問
Can I take Ciprofloxacin with Macimorelin?
MediHelp rates the interaction as major. Ciprofloxacin and Macimorelin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Macimorelin causes a small QT prolongation, and ciprofloxacin also prolongs QT, so the combination may increase arrhythmia risk during the growth hormone stimulation test. The test is single-dose, which limits exposure.
How serious is the interaction between Ciprofloxacin and Macimorelin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Postpone the macimorelin test until ciprofloxacin has been stopped and cleared, or use another diagnostic option. If unavoidable, obtain an ECG and correct electrolytes.
What other medicines interact with Ciprofloxacin?
MediHelp also lists interactions of Ciprofloxacin with, for example, Agomelatine, Fezolinetant, Thioridazine. The full list is on the Ciprofloxacin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
