相互作用
Deflazacort + Sorbitol
重症度: 中等度
Deflazacort and Sorbitol: moderate interaction.
最終更新日
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概要
Sorbitol has an osmotic laxative effect that can cause diarrhea and intestinal potassium loss, and deflazacort, a corticosteroid, can promote renal potassium excretion. Combined use may contribute to hypokalemia, mainly with repeated or large laxative doses.
この相互作用をわかりやすく説明すると
Deflazacort and Sorbitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Deflazacort belongs to Miscellaneous; Sorbitol belongs to Gastrointestinal Tract.
なぜ起こるのか
Additive potassium loss from osmotic diarrhea and corticosteroid mineralocorticoid-related kaliuresis.
対処法
Monitor serum potassium if sorbitol is used repeatedly or in large amounts with deflazacort. Replace potassium as needed.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DeflazacortとSorbitolの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Sorbitolのその他の相互作用
Deflazacortのその他の相互作用
- Adenovirus types 4 and 7 live + Deflazacort 併用禁忌
- Bcg vaccine live + Deflazacort 併用禁忌
- Deflazacort + Influenza virus vaccine quadrivalent intranasal 併用禁忌
- Deflazacort + Measles mumps and rubella vaccine 併用禁忌
- Deflazacort + Measles mumps and rubella vaccine live 併用禁忌
- Deflazacort + Measles mumps rubella and varicella vaccine live 併用禁忌
よくある質問
Can I take Deflazacort with Sorbitol?
MediHelp rates the interaction as moderate. Deflazacort and Sorbitol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sorbitol has an osmotic laxative effect that can cause diarrhea and intestinal potassium loss, and deflazacort, a corticosteroid, can promote renal potassium excretion. Combined use may contribute to hypokalemia, mainly with repeated or large laxative doses.
How serious is the interaction between Deflazacort and Sorbitol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum potassium if sorbitol is used repeatedly or in large amounts with deflazacort. Replace potassium as needed.
What other medicines interact with Sorbitol?
MediHelp also lists interactions of Sorbitol with, for example, Sodium polystyrene sulfonate, Lamivudine. The full list is on the Sorbitol page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
