相互作用
Dexmethylphenidate + Rasagiline
重症度: 併用禁忌
Dexmethylphenidate and Rasagiline: contraindicated interaction.
最終更新日
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概要
Stimulants such as dexmethylphenidate given with MAO inhibitors may cause hypertensive crisis. Labeling contraindicates use during and for 14 days after MAO inhibitor therapy.
この相互作用をわかりやすく説明すると
Dexmethylphenidate and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dexmethylphenidate belongs to Central Nervous System; Rasagiline belongs to Central Nervous System.
なぜ起こるのか
Dexmethylphenidate increases synaptic catecholamines and MAO inhibition prevents their breakdown, causing additive pressor effects.
対処法
Avoid the combination and separate by at least 14 days after stopping the MAO inhibitor. Use a non-stimulant alternative if needed.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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アカウントを作成してPro+トライアルを始めると、DexmethylphenidateとRasagilineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Rasagilineのその他の相互作用
Dexmethylphenidateのその他の相互作用
よくある質問
Can I take Dexmethylphenidate with Rasagiline?
MediHelp rates the interaction as contraindicated. Dexmethylphenidate and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Stimulants such as dexmethylphenidate given with MAO inhibitors may cause hypertensive crisis. Labeling contraindicates use during and for 14 days after MAO inhibitor therapy.
How serious is the interaction between Dexmethylphenidate and Rasagiline?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and separate by at least 14 days after stopping the MAO inhibitor. Use a non-stimulant alternative if needed.
What other medicines interact with Rasagiline?
MediHelp also lists interactions of Rasagiline with, for example, Atomoxetine, Brimonidine, Bupropion-naltrexone. The full list is on the Rasagiline page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
