相互作用
Dihydroergotamine + Eletriptan
重症度: 併用禁忌
Dihydroergotamine and Eletriptan: contraindicated interaction.
最終更新日
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概要
Eletriptan and dihydroergotamine both constrict blood vessels, and together they may produce prolonged vasospasm. Cardiac and cerebral ischemia are the concern.
この相互作用をわかりやすく説明すると
Dihydroergotamine and Eletriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dihydroergotamine belongs to Central Nervous System; Eletriptan belongs to Central Nervous System.
なぜ起こるのか
Additive vasoconstriction via 5-HT1B/1D agonism and ergot vascular receptor effects; dihydroergotamine is also a CYP3A4 substrate.
対処法
Avoid together and separate by at least 24 hours. Use only one agent per attack.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DihydroergotamineとEletriptanの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Eletriptanのその他の相互作用
Dihydroergotamineのその他の相互作用
よくある質問
Can I take Dihydroergotamine with Eletriptan?
MediHelp rates the interaction as contraindicated. Dihydroergotamine and Eletriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Eletriptan and dihydroergotamine both constrict blood vessels, and together they may produce prolonged vasospasm. Cardiac and cerebral ischemia are the concern.
How serious is the interaction between Dihydroergotamine and Eletriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid together and separate by at least 24 hours. Use only one agent per attack.
What other medicines interact with Eletriptan?
MediHelp also lists interactions of Eletriptan with, for example, Almotriptan, Atazanavir, Ceritinib. The full list is on the Eletriptan page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
