相互作用
Ensitrelvir + Voclosporin
重症度: 併用禁忌
Ensitrelvir and Voclosporin: contraindicated interaction.
最終更新日
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概要
Ensitrelvir may substantially increase voclosporin exposure via CYP3A inhibition. This increases risks of nephrotoxicity, hypertension and other calcineurin inhibitor toxicity.
この相互作用をわかりやすく説明すると
Ensitrelvir and Voclosporin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ensitrelvir belongs to Anti Virals; Voclosporin belongs to Miscellaneous.
なぜ起こるのか
Ensitrelvir inhibits CYP3A, reducing voclosporin clearance.
対処法
Avoid the combination; use an alternative COVID-19 therapy.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、EnsitrelvirとVoclosporinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ensitrelvirのその他の相互作用
Voclosporinのその他の相互作用
よくある質問
Can I take Ensitrelvir with Voclosporin?
MediHelp rates the interaction as contraindicated. Ensitrelvir and Voclosporin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ensitrelvir may substantially increase voclosporin exposure via CYP3A inhibition. This increases risks of nephrotoxicity, hypertension and other calcineurin inhibitor toxicity.
How serious is the interaction between Ensitrelvir and Voclosporin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; use an alternative COVID-19 therapy.
What other medicines interact with Ensitrelvir?
MediHelp also lists interactions of Ensitrelvir with, for example, Apalutamide, Carbamazepine, Colchicine. The full list is on the Ensitrelvir page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
