相互作用
Flibanserin + Lenacapavir
重症度: 併用禁忌
Flibanserin and Lenacapavir: contraindicated interaction.
最終更新日
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概要
Lenacapavir is a moderate CYP3A inhibitor and may increase flibanserin exposure. Elevated flibanserin levels raise the risk of hypotension, syncope and sedation.
この相互作用をわかりやすく説明すると
Flibanserin and Lenacapavir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Flibanserin belongs to Genitourinary; Lenacapavir belongs to Anti Virals.
なぜ起こるのか
Inhibition of CYP3A4 reduces flibanserin clearance.
対処法
Avoid the combination in line with the flibanserin restriction on moderate CYP3A4 inhibitors.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、FlibanserinとLenacapavirの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Flibanserinのその他の相互作用
Lenacapavirのその他の相互作用
よくある質問
Can I take Flibanserin with Lenacapavir?
MediHelp rates the interaction as contraindicated. Flibanserin and Lenacapavir are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Lenacapavir is a moderate CYP3A inhibitor and may increase flibanserin exposure. Elevated flibanserin levels raise the risk of hypotension, syncope and sedation.
How serious is the interaction between Flibanserin and Lenacapavir?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in line with the flibanserin restriction on moderate CYP3A4 inhibitors.
What other medicines interact with Flibanserin?
MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
