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相互作用

Flibanserin + Ribociclib

重症度: 併用禁忌

Flibanserin and Ribociclib: contraindicated interaction.

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概要

Ribociclib is a CYP3A4 inhibitor and increases flibanserin exposure. Severe hypotension and syncope can occur.

この相互作用をわかりやすく説明すると

Flibanserin and Ribociclib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Flibanserin belongs to Genitourinary; Ribociclib belongs to Oncology.

エビデンスレベル: Moderate

なぜ起こるのか

CYP3A4 inhibition raising flibanserin exposure

対処法

Do not use together; wait until the inhibitor is out of the system before starting flibanserin.

薬剤師に尋ねること

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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アカウントを作成してPro+トライアルを始めると、FlibanserinとRibociclibの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

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よくある質問

Can I take Flibanserin with Ribociclib?

MediHelp rates the interaction as contraindicated. Flibanserin and Ribociclib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ribociclib is a CYP3A4 inhibitor and increases flibanserin exposure. Severe hypotension and syncope can occur.

How serious is the interaction between Flibanserin and Ribociclib?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use together; wait until the inhibitor is out of the system before starting flibanserin.

What other medicines interact with Flibanserin?

MediHelp also lists interactions of Flibanserin with, for example, Atazanavir, Ceritinib, Clarithromycin. The full list is on the Flibanserin page.

完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで

MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。

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