相互作用
Ibutilide + Ribociclib
重症度: 併用禁忌
Ibutilide and Ribociclib: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Both drugs prolong the QT interval, and ibutilide carries a high risk of torsades de pointes. Combined use compounds this risk.
この相互作用をわかりやすく説明すると
Ibutilide and Ribociclib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ibutilide belongs to Cardiovascular; Ribociclib belongs to Oncology.
なぜ起こるのか
Additive prolongation of cardiac repolarization.
対処法
Do not combine; use an alternative approach to cardioversion or rhythm control.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、IbutilideとRibociclibの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Ribociclibのその他の相互作用
Ibutilideのその他の相互作用
よくある質問
Can I take Ibutilide with Ribociclib?
MediHelp rates the interaction as contraindicated. Ibutilide and Ribociclib are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both drugs prolong the QT interval, and ibutilide carries a high risk of torsades de pointes. Combined use compounds this risk.
How serious is the interaction between Ibutilide and Ribociclib?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not combine; use an alternative approach to cardioversion or rhythm control.
What other medicines interact with Ribociclib?
MediHelp also lists interactions of Ribociclib with, for example, Amiodarone, Cisapride, Dofetilide. The full list is on the Ribociclib page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
