相互作用
Fludrocortisone + Mifepristone
重症度: 併用禁忌
Fludrocortisone and Mifepristone: contraindicated interaction.
最終更新日
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概要
Mifepristone is an antiglucocorticoid, and its labelling for abortion contraindicates long-term corticosteroid therapy because glucocorticoid replacement may be rendered ineffective. Adrenal crisis is a concern in patients taking fludrocortisone with glucocorticoid replacement.
この相互作用をわかりやすく説明すると
Fludrocortisone and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Fludrocortisone belongs to Endocrine; Mifepristone belongs to Endocrine.
なぜ起こるのか
Glucocorticoid receptor blockade reducing replacement efficacy
対処法
Avoid; if mifepristone is essential, coordinate with an endocrinologist and increase glucocorticoid cover as needed.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、FludrocortisoneとMifepristoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Fludrocortisoneのその他の相互作用
- Aldesleukin + Fludrocortisone 重大
- Amphotericin b + Fludrocortisone 重大
- Bcg vaccine live + Fludrocortisone 重大
- Fludrocortisone + Influenza virus vaccine quadrivalent intranasal 重大
- Fludrocortisone + Measles mumps and rubella vaccine live 重大
- Fludrocortisone + Measles mumps rubella and varicella vaccine live 重大
Mifepristoneのその他の相互作用
よくある質問
Can I take Fludrocortisone with Mifepristone?
MediHelp rates the interaction as contraindicated. Fludrocortisone and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mifepristone is an antiglucocorticoid, and its labelling for abortion contraindicates long-term corticosteroid therapy because glucocorticoid replacement may be rendered ineffective. Adrenal crisis is a concern in patients taking fludrocortisone with glucocorticoid replacement.
How serious is the interaction between Fludrocortisone and Mifepristone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid; if mifepristone is essential, coordinate with an endocrinologist and increase glucocorticoid cover as needed.
What other medicines interact with Fludrocortisone?
MediHelp also lists interactions of Fludrocortisone with, for example, Aldesleukin, Amphotericin b, Bcg vaccine live. The full list is on the Fludrocortisone page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
