相互作用
Frovatriptan + Rizatriptan
重症度: 併用禁忌
Frovatriptan and Rizatriptan: contraindicated interaction.
最終更新日
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概要
Frovatriptan and rizatriptan are both 5-HT1B/1D agonists that constrict cranial and coronary vessels. Taken close together, the vasoconstriction is additive and may cause coronary or peripheral vasospasm.
この相互作用をわかりやすく説明すると
Frovatriptan and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Frovatriptan belongs to Central Nervous System; Rizatriptan belongs to Central Nervous System.
なぜ起こるのか
Additive 5-HT1B/1D-mediated vasoconstriction
対処法
Do not use frovatriptan and rizatriptan within 24 hours of each other; choose a single triptan per attack.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
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アカウントを作成してPro+トライアルを始めると、FrovatriptanとRizatriptanの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Rizatriptanのその他の相互作用
Frovatriptanのその他の相互作用
よくある質問
Can I take Frovatriptan with Rizatriptan?
MediHelp rates the interaction as contraindicated. Frovatriptan and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Frovatriptan and rizatriptan are both 5-HT1B/1D agonists that constrict cranial and coronary vessels. Taken close together, the vasoconstriction is additive and may cause coronary or peripheral vasospasm.
How serious is the interaction between Frovatriptan and Rizatriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use frovatriptan and rizatriptan within 24 hours of each other; choose a single triptan per attack.
What other medicines interact with Rizatriptan?
MediHelp also lists interactions of Rizatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Rizatriptan page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
