相互作用
Ergotamine + Frovatriptan
重症度: 併用禁忌
Ergotamine and Frovatriptan: contraindicated interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Ergotamine and frovatriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.
この相互作用をわかりやすく説明すると
Ergotamine and Frovatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ergotamine belongs to Central Nervous System; Frovatriptan belongs to Central Nervous System.
なぜ起こるのか
Additive vasoconstriction through serotonin receptors
対処法
Do not administer within 24 hours of each other.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、ErgotamineとFrovatriptanの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Frovatriptanのその他の相互作用
Ergotamineのその他の相互作用
よくある質問
Can I take Ergotamine with Frovatriptan?
MediHelp rates the interaction as contraindicated. Ergotamine and Frovatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ergotamine and frovatriptan are both vasoconstrictors (ergot alkaloid and 5-HT1B/1D agonist). Together they can cause prolonged vasospasm, with coronary and peripheral ischaemia.
How serious is the interaction between Ergotamine and Frovatriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer within 24 hours of each other.
What other medicines interact with Frovatriptan?
MediHelp also lists interactions of Frovatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Dihydroergotamine. The full list is on the Frovatriptan page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。