相互作用
Dihydroergotamine + Rizatriptan
重症度: 併用禁忌
Dihydroergotamine and Rizatriptan: contraindicated interaction.
最終更新日
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概要
Rizatriptan and dihydroergotamine are both vasoconstrictors, and combined use may cause prolonged vasospasm. Risks include myocardial, cerebral and peripheral ischemia.
この相互作用をわかりやすく説明すると
Dihydroergotamine and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Dihydroergotamine belongs to Central Nervous System; Rizatriptan belongs to Central Nervous System.
なぜ起こるのか
Additive vasoconstriction via 5-HT1B/1D agonism and ergot vascular receptor effects.
対処法
Avoid concurrent use and leave at least 24 hours between doses. Use only one agent per attack.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、DihydroergotamineとRizatriptanの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Rizatriptanのその他の相互作用
Dihydroergotamineのその他の相互作用
よくある質問
Can I take Dihydroergotamine with Rizatriptan?
MediHelp rates the interaction as contraindicated. Dihydroergotamine and Rizatriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Rizatriptan and dihydroergotamine are both vasoconstrictors, and combined use may cause prolonged vasospasm. Risks include myocardial, cerebral and peripheral ischemia.
How serious is the interaction between Dihydroergotamine and Rizatriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and leave at least 24 hours between doses. Use only one agent per attack.
What other medicines interact with Rizatriptan?
MediHelp also lists interactions of Rizatriptan with, for example, Almotriptan, Dihydroergotamine intranasal, Eletriptan. The full list is on the Rizatriptan page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
