相互作用
Ifosfamide + Talimogene laherparepvec
重症度: 併用禁忌
Ifosfamide and Talimogene laherparepvec: contraindicated interaction.
最終更新日
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概要
Talimogene laherparepvec is a live, modified herpes simplex virus that replicates in tissue. In patients immunosuppressed by ifosfamide, this could lead to disseminated or serious herpetic infection.
この相互作用をわかりやすく説明すると
Ifosfamide and Talimogene laherparepvec are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ifosfamide belongs to Oncology; Talimogene laherparepvec belongs to Oncology.
なぜ起こるのか
Immunosuppression from chemotherapy impairs control of the replicating oncolytic herpes virus.
対処法
Do not give talimogene laherparepvec to patients receiving ifosfamide or otherwise immunocompromised. Choose an alternative therapy and consult the oncology team.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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アカウントを作成してPro+トライアルを始めると、IfosfamideとTalimogene laherparepvecの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Ifosfamideのその他の相互作用
Talimogene laherparepvecのその他の相互作用
よくある質問
Can I take Ifosfamide with Talimogene laherparepvec?
MediHelp rates the interaction as contraindicated. Ifosfamide and Talimogene laherparepvec are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Talimogene laherparepvec is a live, modified herpes simplex virus that replicates in tissue. In patients immunosuppressed by ifosfamide, this could lead to disseminated or serious herpetic infection.
How serious is the interaction between Ifosfamide and Talimogene laherparepvec?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give talimogene laherparepvec to patients receiving ifosfamide or otherwise immunocompromised. Choose an alternative therapy and consult the oncology team.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。