相互作用
Insulin glulisine + Rosiglitazone
重症度: 重大
Insulin glulisine and Rosiglitazone: major interaction.
最終更新日
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概要
Rosiglitazone with insulin raises the risk of hypoglycemia and of edema and congestive heart failure. Combined use is generally discouraged because of the cardiovascular fluid-retention risk.
この相互作用をわかりやすく説明すると
Insulin glulisine and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin glulisine belongs to Endocrine; Rosiglitazone belongs to Endocrine.
なぜ起こるのか
Rosiglitazone increases insulin sensitivity, adding to insulin effect, and both promote sodium and fluid retention.
対処法
Avoid in patients with heart failure risk and monitor for edema, rapid weight gain and dyspnea. Reduce insulin if hypoglycemia occurs.
薬剤師に尋ねること
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、Insulin glulisineとRosiglitazoneの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Insulin glulisineのその他の相互作用
Rosiglitazoneのその他の相互作用
- Insulin aspart protamine / insulin aspart + Rosiglitazone 重大
- Insulin aspart-insulin aspart protamine + Rosiglitazone 重大
- Insulin aspart + Rosiglitazone 重大
- Insulin degludec / insulin aspart + Rosiglitazone 重大
- Insulin degludec-insulin aspart + Rosiglitazone 重大
- Insulin degludec-liraglutide + Rosiglitazone 重大
よくある質問
Can I take Insulin glulisine with Rosiglitazone?
MediHelp rates the interaction as major. Insulin glulisine and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone with insulin raises the risk of hypoglycemia and of edema and congestive heart failure. Combined use is generally discouraged because of the cardiovascular fluid-retention risk.
How serious is the interaction between Insulin glulisine and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients with heart failure risk and monitor for edema, rapid weight gain and dyspnea. Reduce insulin if hypoglycemia occurs.
What other medicines interact with Insulin glulisine?
MediHelp also lists interactions of Insulin glulisine with, for example, Alogliptin-pioglitazone, Ethanol, Pentamidine. The full list is on the Insulin glulisine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
