相互作用
Magnesium citrate + Sodium polystyrene sulfonate
重症度: 中等度
Magnesium citrate and Sodium polystyrene sulfonate: moderate interaction.
最終更新日
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概要
Sodium polystyrene sulfonate binds cations in the gut including magnesium, and can cause hypomagnesemia. Magnesium-containing laxatives may also bind to the resin and, with non-absorbable cation exchangers, have been associated with metabolic alkalosis because the resin's buffering of bicarbonate is reduced.
この相互作用をわかりやすく説明すると
Magnesium citrate and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Magnesium citrate belongs to Gastrointestinal Tract; Sodium polystyrene sulfonate belongs to Miscellaneous.
なぜ起こるのか
Cation exchange resin binds magnesium in the gut, and binding of magnesium reduces neutralization of bicarbonate, which can lead to systemic alkalosis.
対処法
Avoid giving magnesium-containing laxatives or antacids with the resin, and separate other oral drugs by at least 3 hours. Monitor serum electrolytes and acid-base status during therapy.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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アカウントを作成してPro+トライアルを始めると、Magnesium citrateとSodium polystyrene sulfonateの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Magnesium citrateのその他の相互作用
Sodium polystyrene sulfonateのその他の相互作用
よくある質問
Can I take Magnesium citrate with Sodium polystyrene sulfonate?
MediHelp rates the interaction as moderate. Magnesium citrate and Sodium polystyrene sulfonate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium polystyrene sulfonate binds cations in the gut including magnesium, and can cause hypomagnesemia. Magnesium-containing laxatives may also bind to the resin and, with non-absorbable cation exchangers, have been associated with metabolic alkalosis because the resin's buffering of bicarbonate is reduced.
How serious is the interaction between Magnesium citrate and Sodium polystyrene sulfonate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid giving magnesium-containing laxatives or antacids with the resin, and separate other oral drugs by at least 3 hours. Monitor serum electrolytes and acid-base status during therapy.
What other medicines interact with Magnesium citrate?
MediHelp also lists interactions of Magnesium citrate with, for example, Ciprofloxacin, Baloxavir marboxil, Bictegravir. The full list is on the Magnesium citrate page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
