相互作用
Omadacycline + Penicillin g procaine-penicillin g
重症度: 中等度
Omadacycline and Penicillin g procaine-penicillin g: moderate interaction.
最終更新日
医療従事者向け・参照専用。このページは簡潔な要約であり、医学的助言ではなく、公式の添付文書や臨床判断に代わるものではありません。処方・調剤の前に必ず確認してください。
このページの臨床コンテンツは英語でのみ提供されています。
概要
Bacteriostatic tetracyclines may blunt the bactericidal activity of beta-lactams, which depend on bacterial growth. Clinical evidence is limited, but reduced penicillin effect is theoretically possible in serious infections.
この相互作用をわかりやすく説明すると
Omadacycline and Penicillin g procaine-penicillin g can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Omadacycline belongs to Anti Bacterial; Penicillin g procaine-penicillin g belongs to Anti Bacterial.
なぜ起こるのか
Protein synthesis inhibition slows bacterial growth, reducing the cell-wall-dependent killing of penicillins.
対処法
Avoid the combination in severe infections such as meningitis or endocarditis where bactericidal action is required. Otherwise monitor clinical response.
薬剤師に尋ねること
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、OmadacyclineとPenicillin g procaine-penicillin gの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
WebでPro+を14日間無料でお試し。カード登録不要。
Penicillin g procaine-penicillin gのその他の相互作用
- Amifampridine + Penicillin g procaine-penicillin g 中等度
- Baricitinib + Penicillin g procaine-penicillin g 中等度
- Cholera vaccine + Penicillin g procaine-penicillin g 中等度
- Microbiota + Penicillin g procaine-penicillin g 中等度
- Penicillin g procaine-penicillin g + Sodium picosulfate / magnesium oxide / anhydrous citric acid 中等度
- Penicillin g procaine-penicillin g + Vadadustat 中等度
Omadacyclineのその他の相互作用
よくある質問
Can I take Omadacycline with Penicillin g procaine-penicillin g?
MediHelp rates the interaction as moderate. Omadacycline and Penicillin g procaine-penicillin g can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Bacteriostatic tetracyclines may blunt the bactericidal activity of beta-lactams, which depend on bacterial growth. Clinical evidence is limited, but reduced penicillin effect is theoretically possible in serious infections.
How serious is the interaction between Omadacycline and Penicillin g procaine-penicillin g?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in severe infections such as meningitis or endocarditis where bactericidal action is required. Otherwise monitor clinical response.
What other medicines interact with Penicillin g procaine-penicillin g?
MediHelp also lists interactions of Penicillin g procaine-penicillin g with, for example, Amifampridine, Baricitinib, Cholera vaccine. The full list is on the Penicillin g procaine-penicillin g page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
