相互作用
Oritavancin + Phenytoin
重症度: 軽度
Oritavancin and Phenytoin: minor interaction.
最終更新日
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このページの臨床コンテンツは英語でのみ提供されています。
概要
Oritavancin is a weak CYP2C9 inhibitor and may modestly raise phenytoin levels. It is given as a single dose, so any effect is likely transient.
この相互作用をわかりやすく説明すると
Oritavancin and Phenytoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Oritavancin belongs to Anti Bacterial; Phenytoin belongs to Central Nervous System.
なぜ起こるのか
Weak inhibition of CYP2C9 by oritavancin reduces phenytoin metabolism.
対処法
Monitor for signs of phenytoin toxicity after oritavancin dosing and check a level if symptoms appear.
薬剤師に尋ねること
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、OritavancinとPhenytoinの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Phenytoinのその他の相互作用
Oritavancinのその他の相互作用
よくある質問
Can I take Oritavancin with Phenytoin?
MediHelp rates the interaction as minor. Oritavancin and Phenytoin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oritavancin is a weak CYP2C9 inhibitor and may modestly raise phenytoin levels. It is given as a single dose, so any effect is likely transient.
How serious is the interaction between Oritavancin and Phenytoin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for signs of phenytoin toxicity after oritavancin dosing and check a level if symptoms appear.
What other medicines interact with Phenytoin?
MediHelp also lists interactions of Phenytoin with, for example, Artemether / lumefantrine, Bictegravir, Cabotegravir. The full list is on the Phenytoin page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
