相互作用
Pentamidine + Trimipramine
重症度: 併用禁忌
Pentamidine and Trimipramine: contraindicated interaction.
最終更新日
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概要
Both agents can prolong the QT interval, and pentamidine has been linked to torsades de pointes. The combination increases the risk of serious ventricular arrhythmia.
この相互作用をわかりやすく説明すると
Pentamidine and Trimipramine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pentamidine belongs to Anti Parasitic; Trimipramine belongs to Central Nervous System.
なぜ起こるのか
Additive QT prolongation.
対処法
Avoid the combination. If pentamidine is necessary, consider interrupting trimipramine and monitor ECG and electrolytes.
薬剤師に尋ねること
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
Pro+会員向け
ページ全体を見る
アカウントを作成してPro+トライアルを始めると、PentamidineとTrimipramineの臨床対応の詳細なアドバイス、追加の注記、エビデンスの詳細、処方全体を対象とした相互作用チェッカーを利用できます。
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
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Trimipramineのその他の相互作用
Pentamidineのその他の相互作用
よくある質問
Can I take Pentamidine with Trimipramine?
MediHelp rates the interaction as contraindicated. Pentamidine and Trimipramine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Both agents can prolong the QT interval, and pentamidine has been linked to torsades de pointes. The combination increases the risk of serious ventricular arrhythmia.
How serious is the interaction between Pentamidine and Trimipramine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination. If pentamidine is necessary, consider interrupting trimipramine and monitor ECG and electrolytes.
What other medicines interact with Trimipramine?
MediHelp also lists interactions of Trimipramine with, for example, Disopyramide, Dofetilide, Ibutilide. The full list is on the Trimipramine page.
完全なモノグラフ、用量、相互作用チェッカーはMediHelpアプリで
MediHelpアプリで、完全なリファレンスを開き、複数薬剤の相互作用をチェックし、用量ツールを利用できます。
