Referência de medicamentos
Pheniramine
Pheniramine is a medicine in the class respiratory. It is used for allergic rhinitis.
- Classe do medicamento: Respiratory
- Indicado para: allergic rhinitis
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Pontos-chave
- Classe do medicamento
- Respiratory
- Formas farmacêuticas comuns
- comprimido, injeção
- Concentrações comuns
- 15 mg/5 ml, 45.5 mg/2 ml, 75 mg
- Interações conhecidas
- 10 (Moderada: 8 · Leve: 2)
- Nomes comerciais
- 3
- Países e mercados
- 2
Para que é usado
Como funciona
Pheniramine competes with histamine for the histamine H1 receptor, reversible competitive inhibitor.
Dose habitual em adultos (resumo da bula)
Inj: 1-2 ml once a day.
Gravidez e amamentação
- Gravidez
- Unknown Older sedating antihistamine (tablets, injection, and eye drops with naphazoline). Human data are limited, with no clear link to birth defects. Loratadine, cetirizine or chlorphenamine have more data and are preferred. Eye drops give low exposure; avoid decongestant combinations early in pregnancy.
- Amamentação
- Unknown Not known if it passes into milk; no LactMed record. Like other sedating antihistamines, regular doses may sedate the infant or reduce milk supply. Prefer loratadine or a small bedtime dose of chlorphenamine; eye drops give low exposure.
Efeitos adversos relatados
- Drowsiness
- Sedation
- Upset Stomach
- Dry Mouth
Contraindicações
- Hypersensitivity to pheniramine, to other antihistamines of similar chemical structure, or to any of the excipients.
- Patients taking monoamine oxidase inhibitors (MAOIs), or within 14 days of stopping them. MAOIs may prolong and intensify the anticholinergic and CNS depressant effects of antihistamines.
- Neonates and premature infants.
Quem deve ter cuidado
- Pheniramine may cause drowsiness, dizziness and blurred vision. Patients should not drive or operate machinery if affected.
- Sedation is increased by alcohol and other CNS depressants, such as hypnotics, anxiolytics, opioids and sedating antidepressants. Avoid alcohol.
- Because of its antimuscarinic effects, use with caution in angle-closure glaucoma, prostatic hypertrophy, urinary retention, bladder neck obstruction and pyloroduodenal obstruction.
Informe ao farmacêutico ou ao médico sobre gravidez ou amamentação, doença renal ou hepática, alergias e todos os outros medicamentos ou suplementos que você usa.
Principais interações (10)
- Amisulpride + Pheniramine Moderate
- Asenapine + Pheniramine Moderate
- Brexpiprazole + Pheniramine Moderate
- Brivaracetam + Pheniramine Moderate
- Cariprazine + Pheniramine Moderate
- Fentanyl + Pheniramine Moderate
- Levetiracetam + Pheniramine Moderate
- Midazolam + Pheniramine Moderate
- Brimonidine + Pheniramine Minor
- Metoclopramide + Pheniramine Minor
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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Outros medicamentos desta classe
Perguntas frequentes
What is Pheniramine used for?
Pheniramine is a medicine in the class respiratory. It is used for Allergic rhinitis, Eczema, Urticaria.
What side effects have been reported with Pheniramine?
Drowsiness, Sedation, Upset Stomach, Dry Mouth.
Can Pheniramine be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Older sedating antihistamine (tablets, injection, and eye drops with naphazoline). Human data are limited, with no clear link to birth defects. Loratadine, cetirizine or chlorphenamine have more data and are preferred. Eye drops give low exposure; avoid decongestant combinations early in pregnancy. Breastfeeding: Unknown. Not known if it passes into milk; no LactMed record. Like other sedating antihistamines, regular doses may sedate the infant or reduce milk supply. Prefer loratadine or a small bedtime dose of chlorphenamine; eye drops give low exposure.
What does Pheniramine interact with?
MediHelp lists 10 known interactions for Pheniramine. Moderate: 8 · Minor: 2. The most serious include Amisulpride, Asenapine, Brexpiprazole.
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