Interações medicamentosas
Fentanyl + Pheniramine
Gravidade: Moderada
Fentanyl and Pheniramine: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Pheniramine is a sedating first-generation antihistamine, and with fentanyl it increases drowsiness and impairs psychomotor performance. Respiratory depression is possible, especially in older or frail patients.
O que esta interação significa em palavras simples
Fentanyl and Pheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Fentanyl belongs to Musculoskeletal; Pheniramine belongs to Respiratory.
Por que acontece
Additive CNS depression via histamine H1 blockade and opioid receptor agonism.
O que fazer
Prefer a non-sedating antihistamine when an antihistamine is needed. If pheniramine is used, monitor for excess sedation and warn against driving and alcohol.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Fentanyl
- Alvimopan + Fentanyl Contraindicada
- Fentanyl + Isocarboxazid Contraindicada
- Fentanyl + Olanzapine / samidorphan Contraindicada
- Fentanyl + Phenelzine Contraindicada
- Fentanyl + Tranylcypromine Contraindicada
- Alfentanil + Fentanyl Grave
Outras interações de Pheniramine
- Amisulpride + Pheniramine Moderada
- Asenapine + Pheniramine Moderada
- Brexpiprazole + Pheniramine Moderada
- Brivaracetam + Pheniramine Moderada
- Cariprazine + Pheniramine Moderada
- Levetiracetam + Pheniramine Moderada
Perguntas frequentes
Can I take Fentanyl with Pheniramine?
MediHelp rates the interaction as moderate. Fentanyl and Pheniramine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Pheniramine is a sedating first-generation antihistamine, and with fentanyl it increases drowsiness and impairs psychomotor performance. Respiratory depression is possible, especially in older or frail patients.
How serious is the interaction between Fentanyl and Pheniramine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Prefer a non-sedating antihistamine when an antihistamine is needed. If pheniramine is used, monitor for excess sedation and warn against driving and alcohol.
What other medicines interact with Fentanyl?
MediHelp also lists interactions of Fentanyl with, for example, Alvimopan, Isocarboxazid, Olanzapine / samidorphan. The full list is on the Fentanyl page.
Monografias completas, posologia e verificador de interações no app MediHelp
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