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Interações medicamentosas

Acarbose + Deflazacort

Gravidade: Moderada

Acarbose and Deflazacort: moderate interaction.

Última atualização

Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Deflazacort, a glucocorticoid, can raise blood glucose and reduce the effectiveness of antidiabetic drugs such as acarbose. Loss of glycemic control may occur, especially with higher doses or prolonged use.

O que esta interação significa em palavras simples

Acarbose and Deflazacort can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Acarbose belongs to Endocrine; Deflazacort belongs to Miscellaneous.

Nível de evidência: Moderate

Por que acontece

Glucocorticoid-induced insulin resistance and increased hepatic gluconeogenesis oppose the glucose-lowering effect of acarbose.

O que fazer

Monitor blood glucose, including postprandial values, when starting or adjusting deflazacort and increase antidiabetic therapy if needed.

O que perguntar ao farmacêutico

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Acarbose with Deflazacort?

MediHelp rates the interaction as moderate. Acarbose and Deflazacort can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Deflazacort, a glucocorticoid, can raise blood glucose and reduce the effectiveness of antidiabetic drugs such as acarbose. Loss of glycemic control may occur, especially with higher doses or prolonged use.

How serious is the interaction between Acarbose and Deflazacort?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose, including postprandial values, when starting or adjusting deflazacort and increase antidiabetic therapy if needed.

What other medicines interact with Acarbose?

MediHelp also lists interactions of Acarbose with, for example, Pramlintide, Asenapine, Bitter melon. The full list is on the Acarbose page.

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