Interações medicamentosas
Aluminum hydroxide + Chenodeoxycholic acid
Gravidade: Moderada
Aluminum hydroxide and Chenodeoxycholic acid: moderate interaction.
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Resumo
Aluminium-containing antacids can adsorb bile acids in the gut. This reduces absorption of chenodeoxycholic acid and may weaken its therapeutic effect.
O que esta interação significa em palavras simples
Aluminum hydroxide and Chenodeoxycholic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Chenodeoxycholic acid belongs to Gastrointestinal Tract.
Por que acontece
Adsorption of bile acid by aluminium hydroxide in the intestinal lumen reduces absorption.
O que fazer
Separate the doses by at least 2 hours. Monitor clinical or biochemical response if concomitant use continues.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Chenodeoxycholic acid
Outras interações de Aluminum hydroxide
Perguntas frequentes
Can I take Aluminum hydroxide with Chenodeoxycholic acid?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Chenodeoxycholic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminium-containing antacids can adsorb bile acids in the gut. This reduces absorption of chenodeoxycholic acid and may weaken its therapeutic effect.
How serious is the interaction between Aluminum hydroxide and Chenodeoxycholic acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate the doses by at least 2 hours. Monitor clinical or biochemical response if concomitant use continues.
What other medicines interact with Chenodeoxycholic acid?
MediHelp also lists interactions of Chenodeoxycholic acid with, for example, Cyclosporin, Sirolimus, Colestipol. The full list is on the Chenodeoxycholic acid page.
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