Interações medicamentosas
Aluminum hydroxide + Tetracycline
Gravidade: Moderada
Aluminum hydroxide and Tetracycline: moderate interaction.
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Resumo
Aluminium antacids markedly reduce absorption of oral tetracycline, which may cause antibiotic failure.
O que esta interação significa em palavras simples
Aluminum hydroxide and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Tetracycline belongs to Anti Bacterial.
Por que acontece
Aluminium cations chelate tetracycline in the gut, forming insoluble, poorly absorbed complexes.
O que fazer
Give tetracycline at least 2 hours before or 4 hours after the antacid. Avoid regular antacid use during the course where feasible.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Aluminum hydroxide
Outras interações de Tetracycline
- Acitretin + Tetracycline Contraindicada
- Methoxyflurane + Tetracycline Contraindicada
- Isotretinoin + Tetracycline Grave
- Palovarotene + Tetracycline Grave
- Strontium ranelate + Tetracycline Grave
- Tetracycline + Tretinoin Grave
Perguntas frequentes
Can I take Aluminum hydroxide with Tetracycline?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Tetracycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminium antacids markedly reduce absorption of oral tetracycline, which may cause antibiotic failure.
How serious is the interaction between Aluminum hydroxide and Tetracycline?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give tetracycline at least 2 hours before or 4 hours after the antacid. Avoid regular antacid use during the course where feasible.
What other medicines interact with Aluminum hydroxide?
MediHelp also lists interactions of Aluminum hydroxide with, for example, Ciprofloxacin, Deferasirox, Dolutegravir. The full list is on the Aluminum hydroxide page.
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