Interações medicamentosas
Aripiprazole + Guanfacine
Gravidade: Moderada
Aripiprazole and Guanfacine: moderate interaction.
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Resumo
Both drugs can lower blood pressure, so the combination can cause dizziness, orthostatic hypotension and syncope. Additive sedation is also possible.
O que esta interação significa em palavras simples
Aripiprazole and Guanfacine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aripiprazole belongs to Central Nervous System; Guanfacine belongs to Cardiovascular.
Por que acontece
Additive hypotensive and sedative effects from central alpha-2 agonism and alpha-1 blockade.
O que fazer
Monitor blood pressure and heart rate, including standing readings, especially at start or dose changes. Advise rising slowly and adjust doses if symptomatic.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Aripiprazole
- Aripiprazole + Pimozide Contraindicada
- Aripiprazole + Thioridazine Contraindicada
- Amisulpride + Aripiprazole Grave
- Aripiprazole + Arsenic trioxide Grave
- Aripiprazole + Calcium / magnesium / potassium / sodium oxybates Grave
- Aripiprazole + Carbamazepine Grave
Outras interações de Guanfacine
- Clonidine + Guanfacine Grave
- Guanfacine + Lofexidine Grave
- Aldesleukin + Guanfacine Moderada
- Amiodarone + Guanfacine Moderada
- Amisulpride + Guanfacine Moderada
- Amitriptyline + Guanfacine Moderada
Perguntas frequentes
Can I take Aripiprazole with Guanfacine?
MediHelp rates the interaction as moderate. Aripiprazole and Guanfacine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can lower blood pressure, so the combination can cause dizziness, orthostatic hypotension and syncope. Additive sedation is also possible.
How serious is the interaction between Aripiprazole and Guanfacine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure and heart rate, including standing readings, especially at start or dose changes. Advise rising slowly and adjust doses if symptomatic.
What other medicines interact with Aripiprazole?
MediHelp also lists interactions of Aripiprazole with, for example, Pimozide, Thioridazine, Amisulpride. The full list is on the Aripiprazole page.
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