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Interações medicamentosas

Bcg vaccine live + Dexamethasone

Gravidade: Contraindicada

Bcg vaccine live and Dexamethasone: contraindicated interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

BCG is a live attenuated bacterial vaccine, and immunosuppression from dexamethasone may allow disseminated BCG infection while reducing vaccine response.

O que esta interação significa em palavras simples

Bcg vaccine live and Dexamethasone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Nível de evidência: Moderate

Por que acontece

Corticosteroid immunosuppression impairs control of live attenuated mycobacteria and reduces vaccine immunogenicity.

O que fazer

Do not give BCG during immunosuppressive dexamethasone therapy; defer until treatment has stopped for the interval recommended by local guidance.

O que perguntar ao farmacêutico

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Bcg vaccine live with Dexamethasone?

MediHelp rates the interaction as contraindicated. Bcg vaccine live and Dexamethasone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. BCG is a live attenuated bacterial vaccine, and immunosuppression from dexamethasone may allow disseminated BCG infection while reducing vaccine response.

How serious is the interaction between Bcg vaccine live and Dexamethasone?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG during immunosuppressive dexamethasone therapy; defer until treatment has stopped for the interval recommended by local guidance.

What other medicines interact with Dexamethasone?

MediHelp also lists interactions of Dexamethasone with, for example, Mifepristone, Rilpivirine, Smallpox vaccine live. The full list is on the Dexamethasone page.

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