Interações medicamentosas
Dexamethasone + Smallpox vaccine live
Gravidade: Contraindicada
Dexamethasone and Smallpox vaccine live: contraindicated interaction.
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Resumo
Live vaccinia vaccine in a patient on immunosuppressive corticosteroids risks progressive vaccinia and other serious complications, along with reduced vaccine response.
O que esta interação significa em palavras simples
Dexamethasone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Glucocorticoid immunosuppression permits uncontrolled replication of live vaccinia virus.
O que fazer
Avoid in patients on immunosuppressive steroid doses outside of a high-risk exposure scenario where specialist advice weighs the risk. Otherwise delay until steroids are stopped and immune function recovers.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Dexamethasone
- Bcg vaccine live + Dexamethasone Contraindicada
- Dexamethasone + Mifepristone Contraindicada
- Dexamethasone + Rilpivirine Contraindicada
- Dexamethasone + Varicella virus vaccine live Contraindicada
- Dexamethasone + Yellow fever vaccine Contraindicada
- Dexamethasone + Zoster vaccine live Contraindicada
Perguntas frequentes
Can I take Dexamethasone with Smallpox vaccine live?
MediHelp rates the interaction as contraindicated. Dexamethasone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live vaccinia vaccine in a patient on immunosuppressive corticosteroids risks progressive vaccinia and other serious complications, along with reduced vaccine response.
How serious is the interaction between Dexamethasone and Smallpox vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients on immunosuppressive steroid doses outside of a high-risk exposure scenario where specialist advice weighs the risk. Otherwise delay until steroids are stopped and immune function recovers.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
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