Interações medicamentosas
Dexamethasone + Yellow fever vaccine
Gravidade: Contraindicada
Dexamethasone and Yellow fever vaccine: contraindicated interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Yellow fever vaccine is a live attenuated virus vaccine. In patients on immunosuppressive doses of dexamethasone it may cause serious vaccine-associated disease, and immunity may be inadequate.
O que esta interação significa em palavras simples
Dexamethasone and Yellow fever vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
Glucocorticoid-induced immunosuppression impairs control of attenuated virus replication and blunts the immune response.
O que fazer
Avoid vaccination during immunosuppressive corticosteroid therapy and for about 1 month after stopping. If travel to an endemic area cannot be avoided, seek a specialist assessment and consider a medical exemption letter.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Dexamethasone
- Bcg vaccine live + Dexamethasone Contraindicada
- Dexamethasone + Mifepristone Contraindicada
- Dexamethasone + Rilpivirine Contraindicada
- Dexamethasone + Smallpox vaccine live Contraindicada
- Dexamethasone + Varicella virus vaccine live Contraindicada
- Dexamethasone + Zoster vaccine live Contraindicada
Perguntas frequentes
Can I take Dexamethasone with Yellow fever vaccine?
MediHelp rates the interaction as contraindicated. Dexamethasone and Yellow fever vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Yellow fever vaccine is a live attenuated virus vaccine. In patients on immunosuppressive doses of dexamethasone it may cause serious vaccine-associated disease, and immunity may be inadequate.
How serious is the interaction between Dexamethasone and Yellow fever vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid vaccination during immunosuppressive corticosteroid therapy and for about 1 month after stopping. If travel to an endemic area cannot be avoided, seek a specialist assessment and consider a medical exemption letter.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
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