Interações medicamentosas
Benazepril + Bismuth subsalicylate
Gravidade: Moderada
Benazepril and Bismuth subsalicylate: moderate interaction.
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Resumo
Salicylate absorbed from bismuth subsalicylate can blunt the blood pressure lowering effect of ACE inhibitors and may add to renal risk, especially in volume depletion, such as during diarrhea. Acute kidney injury is a concern in dehydrated or older patients.
O que esta interação significa em palavras simples
Benazepril and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Benazepril belongs to Cardiovascular; Bismuth subsalicylate belongs to Gastrointestinal Tract.
Por que acontece
Salicylate-mediated inhibition of renal prostaglandins reduces vasodilation and renal perfusion, antagonizing ACE inhibitor effects.
O que fazer
Avoid regular or prolonged use of bismuth subsalicylate. In dehydrated patients monitor renal function, potassium and blood pressure.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Bismuth subsalicylate
- Bismuth subsalicylate + Dichlorphenamide Grave
- Bismuth subsalicylate + Warfarin Grave
- Acetylsalicylic acid + Bismuth subsalicylate Moderada
- Amlodipine-benazepril + Bismuth subsalicylate Moderada
- Aspirin / citric acid / sodium bicarbonate + Bismuth subsalicylate Moderada
- Aspirin rectal + Bismuth subsalicylate Moderada
Outras interações de Benazepril
- Aliskiren + Benazepril Contraindicada
- Benazepril + Sacubitril / valsartan Contraindicada
- Benazepril + Sacubitril-valsartan Contraindicada
- Amifostine + Benazepril Grave
- Amiloride + Benazepril Grave
- Amlodipine-hydrochlorothiazide-valsartan + Benazepril Grave
Perguntas frequentes
Can I take Benazepril with Bismuth subsalicylate?
MediHelp rates the interaction as moderate. Benazepril and Bismuth subsalicylate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Salicylate absorbed from bismuth subsalicylate can blunt the blood pressure lowering effect of ACE inhibitors and may add to renal risk, especially in volume depletion, such as during diarrhea. Acute kidney injury is a concern in dehydrated or older patients.
How serious is the interaction between Benazepril and Bismuth subsalicylate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular or prolonged use of bismuth subsalicylate. In dehydrated patients monitor renal function, potassium and blood pressure.
What other medicines interact with Bismuth subsalicylate?
MediHelp also lists interactions of Bismuth subsalicylate with, for example, Dichlorphenamide, Warfarin, Acetylsalicylic acid. The full list is on the Bismuth subsalicylate page.
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