Interações medicamentosas
Bleomycin + Brentuximab
Gravidade: Contraindicada
Bleomycin and Brentuximab: contraindicated interaction.
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Resumo
Bleomycin causes dose-related pulmonary toxicity, and adding brentuximab vedotin has led to excess pulmonary injury in Hodgkin lymphoma regimens. Cough, dyspnoea and fatal respiratory failure are recorded.
O que esta interação significa em palavras simples
Bleomycin and Brentuximab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Bleomycin belongs to Oncology; Brentuximab belongs to Oncology.
Por que acontece
Additive pulmonary toxicity
O que fazer
Do not use bleomycin together with brentuximab vedotin; use a bleomycin-free regimen (for example AVD with brentuximab) and report new respiratory symptoms promptly.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Brentuximab
Outras interações de Bleomycin
- Adenovirus types 4 and 7 live + Bleomycin Contraindicada
- Bleomycin + Brentuximab vedotin Contraindicada
- Bleomycin + Dengue vaccine Grave
- Bleomycin + Trastuzumab deruxtecan Grave
- Bleomycin + Cholera vaccine Moderada
- Bleomycin + Ethotoin Moderada
Perguntas frequentes
Can I take Bleomycin with Brentuximab?
MediHelp rates the interaction as contraindicated. Bleomycin and Brentuximab are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Bleomycin causes dose-related pulmonary toxicity, and adding brentuximab vedotin has led to excess pulmonary injury in Hodgkin lymphoma regimens. Cough, dyspnoea and fatal respiratory failure are recorded.
How serious is the interaction between Bleomycin and Brentuximab?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use bleomycin together with brentuximab vedotin; use a bleomycin-free regimen (for example AVD with brentuximab) and report new respiratory symptoms promptly.
What other medicines interact with Brentuximab?
MediHelp also lists interactions of Brentuximab with, for example, Dengue vaccine, Etrasimod, Idelalisib. The full list is on the Brentuximab page.
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