Interações medicamentosas
Calcium + Delafloxacin
Gravidade: Moderada
Calcium and Delafloxacin: moderate interaction.
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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
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Resumo
Calcium salts can bind oral delafloxacin in the gut, reducing its absorption and potentially causing treatment failure. The effect is well described for fluoroquinolones with polyvalent cations.
O que esta interação significa em palavras simples
Calcium and Delafloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Calcium belongs to Gastrointestinal Tract; Delafloxacin belongs to Anti Bacterial.
Por que acontece
Chelation of delafloxacin by calcium cations in the gastrointestinal tract, reducing absorption.
O que fazer
Give oral delafloxacin at least 2 hours before or 6 hours after calcium products.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Calcium
- Calcium + Ceftriaxone Contraindicada
- Acalabrutinib + Calcium Moderada
- Alendronate + Calcium Moderada
- Atazanavir + Calcium Moderada
- Baloxavir marboxil + Calcium Moderada
- Bendroflumethiazide + Calcium Moderada
Outras interações de Delafloxacin
- Aluminum hydroxide + Delafloxacin Moderada
- Calcium carbonate + Delafloxacin Moderada
- Carbonyl iron + Delafloxacin Moderada
- Delafloxacin + Didanosine Moderada
- Delafloxacin + Ferrous fumarate Moderada
- Delafloxacin + Ferrous gluconate Moderada
Perguntas frequentes
Can I take Calcium with Delafloxacin?
MediHelp rates the interaction as moderate. Calcium and Delafloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Calcium salts can bind oral delafloxacin in the gut, reducing its absorption and potentially causing treatment failure. The effect is well described for fluoroquinolones with polyvalent cations.
How serious is the interaction between Calcium and Delafloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral delafloxacin at least 2 hours before or 6 hours after calcium products.
What other medicines interact with Calcium?
MediHelp also lists interactions of Calcium with, for example, Ceftriaxone, Acalabrutinib, Alendronate. The full list is on the Calcium page.
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