Interações medicamentosas
Delafloxacin + Didanosine
Gravidade: Moderada
Delafloxacin and Didanosine: moderate interaction.
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Resumo
Buffered didanosine formulations contain aluminum and magnesium that bind delafloxacin and reduce its absorption, risking treatment failure.
O que esta interação significa em palavras simples
Delafloxacin and Didanosine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Delafloxacin belongs to Anti Bacterial; Didanosine belongs to Anti Virals.
Por que acontece
Chelation of delafloxacin by the polyvalent cations in buffered didanosine reduces absorption.
O que fazer
Take delafloxacin at least 2 hours before or 6 hours after buffered didanosine. Use intravenous delafloxacin if separation is impractical.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Delafloxacin
- Aluminum hydroxide + Delafloxacin Moderada
- Calcium carbonate + Delafloxacin Moderada
- Calcium + Delafloxacin Moderada
- Carbonyl iron + Delafloxacin Moderada
- Delafloxacin + Ferrous fumarate Moderada
- Delafloxacin + Ferrous gluconate Moderada
Outras interações de Didanosine
- Didanosine + Elvitegravir / cobicistat / emtricitabine / tenofovir df Contraindicada
- Didanosine + Hydroxycarbamide Contraindicada
- Didanosine + Hydroxyurea Contraindicada
- Didanosine + Ribavirin Contraindicada
- Didanosine + Stavudine Contraindicada
- Allopurinol + Didanosine Grave
Perguntas frequentes
Can I take Delafloxacin with Didanosine?
MediHelp rates the interaction as moderate. Delafloxacin and Didanosine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Buffered didanosine formulations contain aluminum and magnesium that bind delafloxacin and reduce its absorption, risking treatment failure.
How serious is the interaction between Delafloxacin and Didanosine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Take delafloxacin at least 2 hours before or 6 hours after buffered didanosine. Use intravenous delafloxacin if separation is impractical.
What other medicines interact with Delafloxacin?
MediHelp also lists interactions of Delafloxacin with, for example, Aluminum hydroxide, Calcium carbonate, Calcium. The full list is on the Delafloxacin page.
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