Interações medicamentosas
Carbonyl iron + Delafloxacin
Gravidade: Moderada
Carbonyl iron and Delafloxacin: moderate interaction.
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Resumo
Iron binds oral delafloxacin in the gut and markedly reduces its absorption. This can lead to subtherapeutic antibiotic levels and treatment failure.
O que esta interação significa em palavras simples
Carbonyl iron and Delafloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Carbonyl iron belongs to Miscellaneous; Delafloxacin belongs to Anti Bacterial.
Por que acontece
Chelation of delafloxacin by iron cations in the gastrointestinal tract.
O que fazer
Give oral delafloxacin at least 2 hours before or 6 hours after iron products.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Carbonyl iron
- Aluminum hydroxide + Carbonyl iron Moderada
- Baloxavir marboxil + Carbonyl iron Moderada
- Calcium acetate + Carbonyl iron Moderada
- Calcium carbonate + Carbonyl iron Moderada
- Calcium + Carbonyl iron Moderada
- Carbidopa-entacapone-levodopa + Carbonyl iron Moderada
Outras interações de Delafloxacin
- Aluminum hydroxide + Delafloxacin Moderada
- Calcium carbonate + Delafloxacin Moderada
- Calcium + Delafloxacin Moderada
- Delafloxacin + Didanosine Moderada
- Delafloxacin + Ferrous fumarate Moderada
- Delafloxacin + Ferrous gluconate Moderada
Perguntas frequentes
Can I take Carbonyl iron with Delafloxacin?
MediHelp rates the interaction as moderate. Carbonyl iron and Delafloxacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Iron binds oral delafloxacin in the gut and markedly reduces its absorption. This can lead to subtherapeutic antibiotic levels and treatment failure.
How serious is the interaction between Carbonyl iron and Delafloxacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral delafloxacin at least 2 hours before or 6 hours after iron products.
What other medicines interact with Carbonyl iron?
MediHelp also lists interactions of Carbonyl iron with, for example, Aluminum hydroxide, Baloxavir marboxil, Calcium acetate. The full list is on the Carbonyl iron page.
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