Interações medicamentosas
Cefadroxil + Plazomicin
Gravidade: Moderada
Cefadroxil and Plazomicin: moderate interaction.
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Resumo
Plazomicin is an aminoglycoside with nephrotoxic and ototoxic potential, and its labeling advises caution with other nephrotoxic agents. Cephalosporins have been reported to occasionally add to renal injury. Both are renally eliminated, so renal decline raises exposure.
O que esta interação significa em palavras simples
Cefadroxil and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefadroxil belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
Por que acontece
Additive nephrotoxicity with reduced renal clearance of both drugs as kidney function declines.
O que fazer
Monitor serum creatinine and plazomicin levels per labeling, and adjust doses to renal function. Monitor for hearing or vestibular symptoms.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Cefadroxil
- Amikacin + Cefadroxil Moderada
- Avelumab + Cefadroxil Moderada
- Balstilimab + Cefadroxil Moderada
- Bcg vaccine live + Cefadroxil Moderada
- Cefadroxil + Cholera vaccine Moderada
- Cefadroxil + Gentamicin Moderada
Outras interações de Plazomicin
- Cefaclor + Plazomicin Moderada
- Cefalexin + Plazomicin Moderada
- Cefazolin + Plazomicin Moderada
- Cefditoren + Plazomicin Moderada
- Cefepime + Plazomicin Moderada
- Cefixime + Plazomicin Moderada
Perguntas frequentes
Can I take Cefadroxil with Plazomicin?
MediHelp rates the interaction as moderate. Cefadroxil and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin is an aminoglycoside with nephrotoxic and ototoxic potential, and its labeling advises caution with other nephrotoxic agents. Cephalosporins have been reported to occasionally add to renal injury. Both are renally eliminated, so renal decline raises exposure.
How serious is the interaction between Cefadroxil and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin levels per labeling, and adjust doses to renal function. Monitor for hearing or vestibular symptoms.
What other medicines interact with Cefadroxil?
MediHelp also lists interactions of Cefadroxil with, for example, Amikacin, Avelumab, Balstilimab. The full list is on the Cefadroxil page.
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