Interações medicamentosas
Cefazolin + Plazomicin
Gravidade: Moderada
Cefazolin and Plazomicin: moderate interaction.
Última atualização
Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.
O conteúdo clínico desta página está disponível apenas em inglês.
Resumo
Cefazolin given with plazomicin may add to the risk of kidney injury, and plazomicin carries its own risk of nephrotoxicity, ototoxicity and neuromuscular blockade. Impaired renal function would increase plazomicin exposure and toxicity.
O que esta interação significa em palavras simples
Cefazolin and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefazolin belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
Por que acontece
Additive nephrotoxic potential, with reduced aminoglycoside clearance if renal function declines.
O que fazer
Monitor serum creatinine and plazomicin concentrations during combined use. Adjust the plazomicin dose to renal function and monitor for hearing or balance changes.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Para assinantes do Pro+
Desbloqueie a página completa
Crie uma conta e comece um teste do Pro+ para desbloquear a orientação completa de conduta para Cefazolin e Plazomicin, as notas adicionais, os detalhes da evidência e o verificador de interações para uma prescrição completa.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Experimente o Pro+ grátis por 14 dias na web. Sem cartão.
Outras interações de Cefazolin
- Amikacin + Cefazolin Moderada
- Bcg vaccine live + Cefazolin Moderada
- Cefazolin + Cholera vaccine Moderada
- Cefazolin + Dexamethasone-tobramycin Moderada
- Cefazolin + Gentamicin Moderada
- Cefazolin + Kanamycin Moderada
Outras interações de Plazomicin
- Cefaclor + Plazomicin Moderada
- Cefadroxil + Plazomicin Moderada
- Cefalexin + Plazomicin Moderada
- Cefditoren + Plazomicin Moderada
- Cefepime + Plazomicin Moderada
- Cefixime + Plazomicin Moderada
Perguntas frequentes
Can I take Cefazolin with Plazomicin?
MediHelp rates the interaction as moderate. Cefazolin and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefazolin given with plazomicin may add to the risk of kidney injury, and plazomicin carries its own risk of nephrotoxicity, ototoxicity and neuromuscular blockade. Impaired renal function would increase plazomicin exposure and toxicity.
How serious is the interaction between Cefazolin and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin concentrations during combined use. Adjust the plazomicin dose to renal function and monitor for hearing or balance changes.
What other medicines interact with Cefazolin?
MediHelp also lists interactions of Cefazolin with, for example, Amikacin, Bcg vaccine live, Cholera vaccine. The full list is on the Cefazolin page.
Monografias completas, posologia e verificador de interações no app MediHelp
Abra a referência completa, verifique interações entre vários medicamentos e use as ferramentas de posologia no app MediHelp.
