Interações medicamentosas
Certolizumab pegol + Rotavirus oral vaccine live
Gravidade: Contraindicada
Certolizumab pegol and Rotavirus oral vaccine live: contraindicated interaction.
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Resumo
Oral rotavirus vaccine is a live attenuated virus. Infants exposed to certolizumab, such as through breast milk or in utero, or patients treated directly, may be at risk of vaccine-virus infection, though transfer of certolizumab is minimal.
O que esta interação significa em palavras simples
Certolizumab pegol and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Por que acontece
TNF inhibition impairs immune control of replicating live vaccine virus.
O que fazer
Avoid rotavirus vaccine in patients receiving certolizumab. For infants of treated mothers, follow current specialist guidance, as certolizumab has minimal placental and milk transfer.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Certolizumab pegol
- Adenovirus types 4 and 7 live + Certolizumab pegol Contraindicada
- Bcg intravesical live + Certolizumab pegol Contraindicada
- Bcg vaccine live + Certolizumab pegol Contraindicada
- Certolizumab pegol + Influenza virus vaccine quadrivalent intranasal Contraindicada
- Certolizumab pegol + Measles mumps and rubella vaccine Contraindicada
- Certolizumab pegol + Measles mumps and rubella vaccine live Contraindicada
Perguntas frequentes
Can I take Certolizumab pegol with Rotavirus oral vaccine live?
MediHelp rates the interaction as contraindicated. Certolizumab pegol and Rotavirus oral vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oral rotavirus vaccine is a live attenuated virus. Infants exposed to certolizumab, such as through breast milk or in utero, or patients treated directly, may be at risk of vaccine-virus infection, though transfer of certolizumab is minimal.
How serious is the interaction between Certolizumab pegol and Rotavirus oral vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid rotavirus vaccine in patients receiving certolizumab. For infants of treated mothers, follow current specialist guidance, as certolizumab has minimal placental and milk transfer.
What other medicines interact with Certolizumab pegol?
MediHelp also lists interactions of Certolizumab pegol with, for example, Adenovirus types 4 and 7 live, Bcg intravesical live, Bcg vaccine live. The full list is on the Certolizumab pegol page.
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