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Interações medicamentosas

Cimetidine + Vitamin B12

Gravidade: Leve

Cimetidine and Vitamin B12: minor interaction.

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Para profissionais de saúde — apenas referência. Esta página é um resumo breve, não é aconselhamento médico nem substitui a bula oficial ou o julgamento clínico. Verifique sempre antes de prescrever ou dispensar.

O conteúdo clínico desta página está disponível apenas em inglês.

Resumo

Cimetidine reduces gastric acid, which lowers release of B12 from food proteins and may lower absorption with long-term use. Absorption of crystalline oral B12 is less affected, so clinical deficiency is uncommon.

O que esta interação significa em palavras simples

Cimetidine and Vitamin B12 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.

Cimetidine belongs to Gastrointestinal Tract; Vitamin B12 belongs to Gastrointestinal Tract.

Nível de evidência: Moderate

Por que acontece

Reduced gastric acid secretion impairs liberation of protein-bound dietary B12.

O que fazer

Monitor B12 status in long-term users, especially older adults or those with other risk factors. Supplement if levels are low.

O que perguntar ao farmacêutico

  • Is there anything I should notice while taking both?
  • Do I need to tell my doctor at the next visit?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Perguntas frequentes

Can I take Cimetidine with Vitamin B12?

MediHelp rates the interaction as minor. Cimetidine and Vitamin B12 have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Cimetidine reduces gastric acid, which lowers release of B12 from food proteins and may lower absorption with long-term use. Absorption of crystalline oral B12 is less affected, so clinical deficiency is uncommon.

How serious is the interaction between Cimetidine and Vitamin B12?

MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor B12 status in long-term users, especially older adults or those with other risk factors. Supplement if levels are low.

What other medicines interact with Vitamin B12?

MediHelp also lists interactions of Vitamin B12 with, for example, Chloramphenicol, Dichlorphenamide, Metformin. The full list is on the Vitamin B12 page.

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