Interações medicamentosas
Ciprofloxacin + Magnesium sulphate
Gravidade: Moderada
Ciprofloxacin and Magnesium sulphate: moderate interaction.
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Resumo
Oral magnesium-containing products bind ciprofloxacin in the gut and markedly reduce its absorption, potentially causing treatment failure. Intravenous magnesium does not cause this interaction.
O que esta interação significa em palavras simples
Ciprofloxacin and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Ciprofloxacin belongs to Anti Bacterial; Magnesium sulphate belongs to Cardiovascular.
Por que acontece
Chelation of ciprofloxacin by divalent magnesium cations in the gastrointestinal tract forms poorly absorbed complexes.
O que fazer
Give oral ciprofloxacin at least 2 hours before or 6 hours after oral magnesium. Use an alternative if separation is not feasible.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Magnesium sulphate
- Amikacin + Magnesium sulphate Moderada
- Amphotericin b deoxycholate + Magnesium sulphate Moderada
- Atracurium + Magnesium sulphate Moderada
- Baloxavir marboxil + Magnesium sulphate Moderada
- Cisatracurium + Magnesium sulphate Moderada
- Delafloxacin + Magnesium sulphate Moderada
Outras interações de Ciprofloxacin
- Agomelatine + Ciprofloxacin Contraindicada
- Ciprofloxacin + Fezolinetant Contraindicada
- Ciprofloxacin + Thioridazine Contraindicada
- Ciprofloxacin + Tizanidine Contraindicada
- Ciprofloxacin + Vandetanib Contraindicada
- Alosetron + Ciprofloxacin Grave
Perguntas frequentes
Can I take Ciprofloxacin with Magnesium sulphate?
MediHelp rates the interaction as moderate. Ciprofloxacin and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Oral magnesium-containing products bind ciprofloxacin in the gut and markedly reduce its absorption, potentially causing treatment failure. Intravenous magnesium does not cause this interaction.
How serious is the interaction between Ciprofloxacin and Magnesium sulphate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give oral ciprofloxacin at least 2 hours before or 6 hours after oral magnesium. Use an alternative if separation is not feasible.
What other medicines interact with Magnesium sulphate?
MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.
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