Interações medicamentosas
Amphotericin b deoxycholate + Magnesium sulphate
Gravidade: Moderada
Amphotericin b deoxycholate and Magnesium sulphate: moderate interaction.
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Resumo
Amphotericin B deoxycholate causes renal tubular injury with magnesium wasting, leading to hypomagnesemia. This can reduce the effect of magnesium supplementation and cause cardiac and neuromuscular problems.
O que esta interação significa em palavras simples
Amphotericin b deoxycholate and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Por que acontece
Amphotericin-induced tubular damage increases urinary magnesium excretion.
O que fazer
Monitor serum magnesium, potassium and renal function, and increase magnesium replacement as required.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Magnesium sulphate
- Amikacin + Magnesium sulphate Moderada
- Atracurium + Magnesium sulphate Moderada
- Baloxavir marboxil + Magnesium sulphate Moderada
- Ciprofloxacin + Magnesium sulphate Moderada
- Cisatracurium + Magnesium sulphate Moderada
- Delafloxacin + Magnesium sulphate Moderada
Perguntas frequentes
Can I take Amphotericin b deoxycholate with Magnesium sulphate?
MediHelp rates the interaction as moderate. Amphotericin b deoxycholate and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amphotericin B deoxycholate causes renal tubular injury with magnesium wasting, leading to hypomagnesemia. This can reduce the effect of magnesium supplementation and cause cardiac and neuromuscular problems.
How serious is the interaction between Amphotericin b deoxycholate and Magnesium sulphate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum magnesium, potassium and renal function, and increase magnesium replacement as required.
What other medicines interact with Magnesium sulphate?
MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Atracurium, Baloxavir marboxil. The full list is on the Magnesium sulphate page.
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