Interações medicamentosas
Cisatracurium + Magnesium sulphate
Gravidade: Moderada
Cisatracurium and Magnesium sulphate: moderate interaction.
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Resumo
Parenteral magnesium sulfate enhances the effect of cisatracurium, leading to a deeper and longer neuromuscular block. Delayed recovery may prolong ventilatory support.
O que esta interação significa em palavras simples
Cisatracurium and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cisatracurium belongs to Musculoskeletal; Magnesium sulphate belongs to Cardiovascular.
Por que acontece
Magnesium decreases presynaptic acetylcholine release and reduces postjunctional sensitivity, adding to competitive neuromuscular blockade.
O que fazer
Use reduced cisatracurium doses and monitor neuromuscular function with train-of-four. Anticipate prolonged recovery.
O que perguntar ao farmacêutico
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Outras interações de Magnesium sulphate
- Amikacin + Magnesium sulphate Moderada
- Amphotericin b deoxycholate + Magnesium sulphate Moderada
- Atracurium + Magnesium sulphate Moderada
- Baloxavir marboxil + Magnesium sulphate Moderada
- Ciprofloxacin + Magnesium sulphate Moderada
- Delafloxacin + Magnesium sulphate Moderada
Outras interações de Cisatracurium
Perguntas frequentes
Can I take Cisatracurium with Magnesium sulphate?
MediHelp rates the interaction as moderate. Cisatracurium and Magnesium sulphate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Parenteral magnesium sulfate enhances the effect of cisatracurium, leading to a deeper and longer neuromuscular block. Delayed recovery may prolong ventilatory support.
How serious is the interaction between Cisatracurium and Magnesium sulphate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use reduced cisatracurium doses and monitor neuromuscular function with train-of-four. Anticipate prolonged recovery.
What other medicines interact with Magnesium sulphate?
MediHelp also lists interactions of Magnesium sulphate with, for example, Amikacin, Amphotericin b deoxycholate, Atracurium. The full list is on the Magnesium sulphate page.
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