Interações medicamentosas
Cisapride + Hydroxychloroquine
Gravidade: Contraindicada
Cisapride and Hydroxychloroquine: contraindicated interaction.
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Resumo
Hydroxychloroquine can prolong the QT interval and, with cisapride, increases the risk of torsades de pointes.
O que esta interação significa em palavras simples
Cisapride and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Cisapride belongs to Gastrointestinal Tract; Hydroxychloroquine belongs to Musculoskeletal.
Por que acontece
Additive inhibition of cardiac potassium channels with QT prolongation.
O que fazer
Avoid the combination and use an alternative prokinetic. If unavoidable, monitor the ECG and keep potassium and magnesium within normal limits.
O que perguntar ao farmacêutico
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Outras interações de Cisapride
- Apomorphine + Cisapride Contraindicada
- Artemether + Cisapride Contraindicada
- Azithromycin + Cisapride Contraindicada
- Ceritinib + Cisapride Contraindicada
- Chloroquine + Cisapride Contraindicada
- Cisapride + Citalopram Contraindicada
Outras interações de Hydroxychloroquine
- Arsenic trioxide + Hydroxychloroquine Contraindicada
- Dronedarone + Hydroxychloroquine Contraindicada
- Hydroxychloroquine + Pimozide Contraindicada
- Hydroxychloroquine + Thioridazine Contraindicada
- Hydroxychloroquine + Vandetanib Contraindicada
- Adagrasib + Hydroxychloroquine Grave
Perguntas frequentes
Can I take Cisapride with Hydroxychloroquine?
MediHelp rates the interaction as contraindicated. Cisapride and Hydroxychloroquine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Hydroxychloroquine can prolong the QT interval and, with cisapride, increases the risk of torsades de pointes.
How serious is the interaction between Cisapride and Hydroxychloroquine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and use an alternative prokinetic. If unavoidable, monitor the ECG and keep potassium and magnesium within normal limits.
What other medicines interact with Cisapride?
MediHelp also lists interactions of Cisapride with, for example, Apomorphine, Artemether, Azithromycin. The full list is on the Cisapride page.
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